Error in Information Processing
Venue: SSCU Auditorium

Accurate transfer of information at molecular level takes place with the help of a copying machine and an information 
template, which is generally duplicated. The copying machine is designed in such a way that it can copy information 
at relevant speeds and minimize errors by discriminating between right and wrong information with high precision.
 The equilibrium binding and random co-polymerisation models developed based on thermodynamic principles to 
understand the accuracy of the copying machines will be discussed. A new model, which was developed by combining
 both the models to overcome their drawbacks will be presented. Finally, considering the irreversible nature of 
the copying procedure I will discuss the principles of non-equilibrium thermodynamics for template assisted information

1. J. J. Hopfield, Kinetic proofreading: A new mechanism for reducing error in biosynthetic
   processes requiring high specificity, Proc. Natl. Acad. Sci. U.S.A 71, 4135 (1974)
2. C. H. Bennet, The thermodynamics of computation – A review, Int. J. Theor. Phys. 21, 905
3. P. Sartori and S. Pigolotti, Kinetic versus energetic discrimination in biological
   copying, Phys. Rev. Lett. 110, 188101 (2013)
4. P. Sartori and S. Pigolotti, Thermodynamics of error correction, Phys. Rev. X, 5, 041039

All are cordially invited to attend