Special Seminar
Name: Dr. Arnab Maity
Affiliation: Department of Chemical Engineering, Technion, Israel
Title: “Advanced Solid State Chemical Detectors for Non-destructive Molecular Cancer Biopsy, Chiral Recognition, Heavy Metals, Microorganisms, Obnoxious Gas and Organic Compounds”
Date & Time: Friday, 02nd August at 11.00 a.m.
Venue: Rajarshi Bhattacharya Memorial Lecture Hall, Chemical Sciences Building
Abstract:
This talk introduces a cutting-edge approach to the synthesis and nanofabrication of bio-chemical ligand modified 2D material-based inkjet-printed solid state chemical detectors with spatiotemporal control, heralding innovative advancements in machine-intelligence-controlled cancer research, molecular cancer profiling, environmental monitoring, transient biodegradable printed nano-electronics on paper, and transistor (FET) technology [1-3]. Drawing inspiration from the intricate architecture of butterfly wings, we have engineered a hierarchical stacked geometrical configuration (HSGC) utilizing functionalized graphene layers and helical cellulose-based sieves. This innovative design enables time-resolved separation and detection of individual molecules within a mixture, producing detailed mass spectrograms. This breakthrough opens up numerous possibilities, including real-time volatile organic compounds (VOC) spectrograms during machine learning-enabled liquid cancer biopsies, predicting the mutation status of growing cancer organoids using advanced generative AI, and eliminating the need for complex procedures in chiral molecule recognition. Imagine wearable biocompatible and biodegradable transient electronic devices that capture molecular profiles emitted from the skin under various dietary conditions, offering personalized health insights. Moreover, spin-sensitive detectors constructed from chiral and DNA-like helical nano-hybrids of 2D materials offer exciting possibilities for identifying chiral molecules. This advancement could pave the way for a new era of organic quantum chiral and helical spintronics and computing. Additionally, the talk will explore the potential of various 2D materials, such as graphene and black phosphorus, used in ultrafast field-effect transistors (FETs) for detecting heavy metals and toxic ions (lead, mercury, arsenic, phosphates, etc.) and microorganisms (E. coli bacteria, Ebola virus, etc.) in aquatic samples. An in-depth discussion will cover industry-inspired non-destructive testing, minimizing device variation, scalability, and technology readiness levels (TRL) [4]. We will also highlight exciting applications of nano-ceramics in automotive and torpedo air quality monitoring and heavy metal removal. This presentation promises a captivating journey into the future of 2D material and nano-ceramic based detection, demonstrating its revolutionary potential to transform medical and environmental monitoring, Organic Chiral Spintronics, sustainable biodegradable electronic devices, biocompatible implants for brain-machine interfaces, harmful nuclear leak and radiological substance detection, pharmaceuticals chemical, agrochemicals, and nanotechnological advancements for the betterment of our world.
References:
[1] Maity A. … and Haick, H. Ultra-Fast Portable and Wearable Sensing Design for Continuous and Wide-Spectrum Molecular Analysis and Diagnostics. Advanced Science 2022; 9(34), e2203693.
[2] Maity, A., … and Haick, H. Helical (2023), Quantum Spin-Controlled Sieve Chiral Spectrometer. Advanced Materials 2023, e2209125. 10.1002/adma.202209125.
[3] Maity, (2022), Gate-Controlled Chiral Recognition and Spin Assessment with All-Electric Hybrid Quantum Wire-Based Transistors. Small, 2022 Dec 9;e2205038.
[4] Maity, A.,.. Chen. J. Scalable graphene sensor array for real-time toxins monitoring in flowing water, Nature Communication 14, 4184 (2023). doi: 10.1038/s41467-023-39701-0.